Clashes broke out on Dokki's Tahrir Street between supporters of deposed President Mohamed Mursi and the area's residents near Assad Ibn al-Forat Mosque, the Middle East News Agency reported on Friday.
Mursi's supporters attempted to rally for marches but the residents stood up to them.
Nile News channel aired live footage showing a pro-Mursi march on the May 15 Bridge headed to Boulaq Abul Ela area.
Two armed demonstrators were seen firing at residential buildings.
Security forces tear-gassed the protesters on the bridge.
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